USING SIBLINGS FOR THE STUDY OF EARLY-LIFE ECONOMIC DETERMINANTS OF TYPE-2 DIABETES
Viola Angelini, Rob Alessie, Gerard van den Berg, Jochen Mierau e Gianmaria Niccodemi
We study the effects of economic conditions early in life on the occurrence of type-2 diabetes in adulthood using contextual economic conditions and within-sibling pair variation. We use data from Lifelines: a longitudinal cohort study and biobank including 51,270 siblings born in the Netherlands from the 1950s onward. Sibling fixed-effects account for selective fertility. To identify type-2 diabetes we use biomarkers on the hemoglobin A1c concentration and fasting glucose in the blood.
We find that worse economic conditions around birth increase the probability of type-2 diabetes later in life both in males and in females. Moreover, not accounting for selective fertility and/or relying on self-reported diabetes leads to biased inference.